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A myriad of things can affect your DAO enzyme or histamine levels, including: Medications: Some medications can block DAO functions or prevent production Genetics: Some individuals have a genetic mutation that causes the body to produce less DAO or dysfunctional DAO Diet: Foods rich in histamine can cause DAO enzymes to function incorrectly GI Disorders: Certain GI disorders, like inflammatory bowel disease, can cause DAO insufficiency Overgrowth of Bacteria: Bacteria grow when your body cant digest food properly, causing too much histamine production Which body systems can a histamine intolerance affect

[186] suggested that Dendrobium nobile extract improved Treg cell differentiation, inhibited the PI3K/AKT/mTOR pathway, and suppressed inflammation in AR mice

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